The story of musician Dewey Cox (John C. Reilly), whose songs would change a nation. On his rock ‘n roll spiral, Cox sleeps with 411 women, marries 3 times, has 22 kids and 14 stepkids, stars in his own 70s TV show, collects friends ranging from Elvis to The Beatles to a chimp, and gets addicted to – and then kicks – every drug known to man… but despite it all, Cox grows into a national icon and eventually earns the love of a good woman – longtime backup singer Darlene (Jenna Fischer).
